The Alzheimer’s Disease Research Center (ADRC) hosted its fourth annual Participant Appreciation Day on May 11, 2011. Our staff was joined by 58 participants and caregivers. Following a warm welcome by Margaret Sewell, Ph.D., presentations included information about genetics, new treatment approaches, and the experience of participating in a clinical research trial. Sam Gandy, M.D., Ph.D., the Associate Director of the ADRC, discussed the process of developing new medications. Gregory Elder, M.D., reviewed what genetic studies have told us about Alzheimer’s disease. Mary Sano, Ph.D., the Director of the ADRC, delved into the benefits of participating in research. Information about our current clinical research trials was presented by Hillel Grossman, M.D., and Judith Neugroschl, M.D. In addition, Laurel Humble, from the Museum of Modern Art (MoMA), joined us for a presentation about the Art and Dementia Program at the MoMA. She also conducted a break-out session where participants created personal masterpieces from paper cut-outs. Meanwhile, Elizabeth Fine, MSW, informed caregivers on various sources of support.